Postdoc in muscle cell biology and cardiovascular research

About the research project

The project pursues molecular mechanisms underlying the development of cardiomyopathy and heart failure. We use genetically engineered (e.g. gene knockout) and environmentally induced (e.g. high fat diet) animal models to mimic heart failure forms found in patients. Of specific interest are pathological alterations in cardiac signalling pathways, which lead to altered gene programs, and changed posttranslational modifications in cardiac substrate proteins. Another focus forms deciphering cellular effects of autocrine and/or paracrine signalling by nitric oxide, stemming either from cardiac endothelial cells or cardiomyocytes.

Your job responsibilities

As Postdoc in muscle cell biology and cardiovascular research, your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.

• Independent research of high international quality, including publication and grant applications.
• Support of ongoing research projects in the laboratory.
• Help in the supervision of at least one PhD student or junior scientist in the lab.
• Help in the organization of the laboratory.
• Present our work at national and international meetings, conferences, or workshops.
• You may also be asked to support teaching activities.

You will report to Dr. Stephan Lange, and the Head of Department for Biomedicine.

Your competences

You have academic qualifications at PhD level, for example within the following areas insert areas. Biomedical Research, Genetics, Biochemistry, Molecular Biology, Cell Biology, Cardiac or Skeletal Muscle Physiology and/or Bioinformatics. Expertise in cardiac and skeletal muscle physiology (e.g. echocardiography, force measurements), spatial transcriptomics and/or other NGS techniques, cell biology (isolation and culture of primary rodent and human cells, standard cell culture, immunofluorescence, calcium imaging, culture and differentiation of iPSC into cardiomyocytes) and biochemistry (standard RNA, DNA and protein analyses, proteomics, proximity ligation assays - use of BioID2 or TurboID) is advantageous. Experience with animal work (rodent models) is desirable.

As a person, you have good interpersonal skills, are inclusive and team-oriented and able to contribute to a good work environment. We expect you to be fluent in oral and written English.

In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.

Questions about the position

If you have any questions about the position, please contact Dr. Stephan Lange by phone: +45 81506554

Your place of work will be the Department of Department of Biomedicine, Skou Building, Høegh-Guldbergs Gade 10, C. F. Møllers Allé 6, 8000 Aarhus C, Denmark. Some work may be performed at the Steno Diabetes Center Aarhus.

We expect to conduct interviews starting week 16, 2026.

Terms of employment

• Appointment as a postdoc requires academic qualifications at PhD level.
• Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities.
• The appointment is in accordance with the Danish Confederation of Professional Associations (Akademikerne).
• Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health.